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The cell cycle and interphase (G1, S, G2, M)

What the cell does between divisions. The phases in order, where DNA is duplicated and why interphase is not a 'resting phase'.

Direct answer: The cell cycle has two main stages: interphase (G1 growth, S synthesis/DNA replication and G2 preparation) and the M phase (mitosis + cytokinesis). DNA is duplicated in the S phase, not during mitosis.

Phases of the cell cycle

PhaseWhat happens
G1The cell grows and makes proteins and organelles.
SDNA replicates: each chromosome ends up with 2 chromatids.
G2Final growth and preparation to divide.
MMitosis (DNA distribution) + cytokinesis (cytoplasm division).

Checkpoints and G0

The cycle has checkpoints (G1/S, G2/M) that verify everything is correct before continuing. Some cells leave the cycle into a resting state called G0 (for example, neurons).

Exam trap: DNA is duplicated in the S phase (interphase), NOT in mitosis. In mitosis the already-duplicated DNA is only distributed. And interphase is not "resting": it is the most active and longest stage.

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Frequently asked questions

What are the phases of the cell cycle?

Interphase (G1, S, G2) and the M phase (mitosis and cytokinesis).

In which phase does DNA replicate?

In the S phase of interphase.

Is interphase a resting phase?

No. It is the longest and most active stage; the cell grows and duplicates its DNA.